Targeted labeling of an early-stage tumor spheroid in a chorioallantoic membrane model with upconversion nanoparticles.
نویسندگان
چکیده
In vivo detection of cancer at an early-stage, i.e. smaller than 2 mm, is a challenge in biomedicine. In this work target labeling of an early-stage tumor spheroid (∼500 μm) is realized for the first time in a chick embryo chorioallantoic membrane (CAM) model with monoclonal antibody functionalized upconversion nanoparticles (UCNPs-mAb).
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ورودعنوان ژورنال:
- Nanoscale
دوره 7 5 شماره
صفحات -
تاریخ انتشار 2015